CLTA antibody (C-Term)

Catalog No. ABIN2788075

Product Details anti-CLTA Antibody

Target: CLTA (Clathrin, Light Chain A (CLTA))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLTA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KELEEWYARQ DEQLQKTKAN NRAAEEAFVN DIDESSPGTE WERVARLCDF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against CLTA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLTA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 218 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CLTA

Target: CLTA (Clathrin, Light Chain A (CLTA))

Alternative Name: CLTA (CLTA Products)

Synonyms: lca antibody, zgc:73358 antibody, wu:fb61d08 antibody, wu:fj48d06 antibody, CLTA antibody, DDBDRAFT_0169251 antibody, DDBDRAFT_0191305 antibody, DDB_0169251 antibody, DDB_0191305 antibody, clc antibody, LCA antibody, LCA1 antibody, LCA2 antibody, LCA3 antibody, CLTA2 antibody, AV026556 antibody, Clathrin light chain antibody, clathrin light chain A antibody, clathrin, light chain A antibody, clathrin, light chain (Lca) antibody, clathrin light chain antibody, clathrin, light polypeptide (Lca) antibody, clic-1 antibody, clta antibody, CLTA antibody, CNI00580 antibody, LOC5567495 antibody, CLC1 antibody, CpipJ_CPIJ018056 antibody, PTRG_01988 antibody, PMAA_096950 antibody, SJAG_04517 antibody, TSTA_044110 antibody, PAS_chr1-4_0158 antibody, clc antibody, Clta antibody

Background: Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 8 and 12.
Alias Symbols: LCA
Protein Interaction Partner: TP53, UBC, EGFR, PAN2, MYBL2, VCAM1, RGS2, ITGA4, FN1, CFTR, VCP, MAD2L2, SYNJ1, COPS5, CUL3, ARRB2, ARRB1, MAP1LC3B, TNK2, HSPA8, MAP1LC3A, STAMBP, HIP1R, HIP1, CLTC,
Protein Size: 218

Molecular Weight: 24 kDa

Gene ID: 1211

NCBI Accession: NM_001833, NP_001824

UniProt: P09496

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation