POFUT1 antibody (Middle Region)

Catalog No. ABIN2788068

Product Details anti-POFUT1 Antibody

Target: POFUT1 (Protein O-Fucosyltransferase 1 (POFUT1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POFUT1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RVISLEDFME KLAPTHWPPE KRVAYCFEVA AQRSPDKKTC PMKEGNPFGP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against POFUT1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human POFUT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 388 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for POFUT1

Target: POFUT1 (Protein O-Fucosyltransferase 1 (POFUT1))

Alternative Name: POFUT1 (POFUT1 Products)

Synonyms: fut12 antibody, zgc:110472 antibody, o-fut antibody, o-fuc-t antibody, o-fuct-1 antibody, pofut1 antibody, DDD2 antibody, FUT12 antibody, O-FUT antibody, O-Fuc-T antibody, O-FucT-1 antibody, OFUCT1 antibody, mKIAA0180 antibody, Fut12 antibody, protein O-fucosyltransferase 1 antibody, POFUT1 antibody, pofut1 antibody, Pofut1 antibody

Background: This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: FUT12, KIAA0180, MGC2482, O-FUT, O-Fuc-T, O-FucT-1
Protein Interaction Partner: UBC, NEDD8, FBXO6, AKT2, NNT, H2AFX, DLL1, JAG1, NOTCH1,
Protein Size: 388

Molecular Weight: 41 kDa

Gene ID: 23509

NCBI Accession: NM_015352, NP_056167

UniProt: Q6EV69

Pathways: Notch Signaling, SARS-CoV-2 Protein Interactome