VCP antibody (C-Term)

Catalog No. ABIN2788042

Product Details anti-VCP Antibody

Target: VCP (Valosin Containing Protein (VCP))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VCP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Sequence: EMFAQTLQQS RGFGSFRFPS GNQGGAGPSQ GSGGGTGGSV YTEDNDDDLY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against VCP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human VCP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 806 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VCP

Target: VCP (Valosin Containing Protein (VCP))

Alternative Name: VCP (VCP Products)

Background: The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.
Alias Symbols: IBMPFD, MGC131997, MGC148092, MGC8560, TERA, p97, ALS14
Protein Interaction Partner: AMFR, UBXN2B, CEP19, FAM104A, UBC, ATXN3, FUS, DTNB, WDYHV1, VCP, LNX1, PSMA1, UBXN1, ASPSCR1, NSFL1C, RPL9, UBOX5, HUWE1, ISG15, ATG5, PLAA, RNF8, YOD1, VAPA, RPL23, GTF3C5, ACTB, PPP3CA, PPM1B, PHKG2, MDM2, CDK2, CCNB1, AR, OTU1, TUBB, UBXN2A, H2AFV, FB
Protein Size: 806

Molecular Weight: 89 kDa

Gene ID: 7415

NCBI Accession: NM_007126, NP_009057

UniProt: P55072

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway