PSMC6 antibody (C-Term)
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- Target See all PSMC6 Antibodies
- PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Horse, Rabbit, Dog, Guinea Pig, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMC6 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GFNGADLRNV CTEAGMFAIR ADHDFVVQED FMKAVRKVAD SKKLESKLDY
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PSMC6. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human PSMC6
- Top Product
- Discover our top product PSMC6 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 389 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))
- Alternative Name
- PSMC6 (PSMC6 Products)
- Synonyms
- DDBDRAFT_0186051 antibody, DDBDRAFT_0232968 antibody, DDB_0186051 antibody, DDB_0232968 antibody, fb20g04 antibody, wu:fb20g04 antibody, wu:fc85c10 antibody, cadp44 antibody, sug2 antibody, PSMC6 antibody, psmc6-a antibody, NV13405 antibody, CADP44 antibody, P44 antibody, SUG2 antibody, p42 antibody, 2300001E01Rik antibody, AI451058 antibody, 26S protease regulatory subunit S10B antibody, 26S proteasome regulatory subunit 10B antibody, proteasome 26S subunit, ATPase 6 antibody, proteasome 26S subunit, ATPase 6 L homeolog antibody, 26S protease regulatory subunit 10B antibody, proteasome 26S subunit, ATPase 6 S homeolog antibody, proteasome (prosome, macropain) 26S subunit, ATPase, 6 antibody, ATEG_02903 antibody, HCAG_04181 antibody, LOC5565051 antibody, EDI_289460 antibody, CpipJ_CPIJ003334 antibody, EHI_194070 antibody, PTRG_02716 antibody, BDBG_01801 antibody, psmC6 antibody, MCYG_07206 antibody, PITG_00229 antibody, VDBG_04729 antibody, MGYG_04704 antibody, TERG_01608 antibody, DICPUDRAFT_97252 antibody, Tsp_02519 antibody, prs10 antibody, LOC100282100 antibody, Psmc6 antibody, psmc6 antibody, psmc6.L antibody, PSMC6 antibody, LOC693577 antibody, psmc6.S antibody, LOC100117671 antibody
- Background
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
Alias Symbols: CADP44, MGC12520, P44, SUG2, p42
Protein Interaction Partner: SDCBP, CCDC146, CYB5R2, HUWE1, UBC, PSMD9, PSMC6, PSMC3, SUMO2, STAU1, PSMD14, MDM2, ABCF1, UBR4, ADRM1, TXNL1, AIMP1, AIMP2, RPS21, RPS15A, RPS12, RPS8, QARS, PSMD12, PSMD11, PSMD8, PSMD4, UCHL5, DYNC1LI1, PSMD3, PSMD2, PSMD1, PSMC5, PSMC2, PSMC1, PARK2,
Protein Size: 389 - Molecular Weight
- 44 kDa
- Gene ID
- 5706
- NCBI Accession
- NM_002806, NP_002797
- UniProt
- P62333
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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