USP1 antibody (C-Term)

Catalog No. ABIN2788015

Product Details anti-USP1 Antibody

Target: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SETSDTTGTH ESDRNKESSD QTGINISGFE NKISYVVQSL KEYEGKWLLF

Predicted Reactivity: Cow: 92%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against USP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human USP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 785 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for USP1

Target: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Alternative Name: USP1 (USP1 Products)

Synonyms: usp1-a antibody, UBP antibody, ubiquitin specific peptidase 1 antibody, ubiquitin specific peptidase 1 S homeolog antibody, USP1 antibody, usp1.S antibody, Usp1 antibody

Background: This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.
Alias Symbols: UBP
Protein Interaction Partner: WDR48, UBC, DTX3, TRIM46, PHF7, TRAF6, UBE2A, UNC45A, VPS36, WDR5, VPS26A, CSE1L, PHLPP1, PCNA, SUMO2, ATAD5, ID2, FANCD2, USP1, DSG1, DSC1, CALML3, ANXA2P2, ALDH16A1, CALML5, PHLPP2, TAGLN2, USP4, PKP1, MYH9, LYZ, LGALS7, KRT17, KRT4, KPNA1, JUP, HSPB1,
Protein Size: 785

Molecular Weight: 88 kDa

Gene ID: 7398

NCBI Accession: NM_003368, NP_003359

UniProt: O94782