CDC26 antibody (Middle Region)

Catalog No. ABIN2787995

Product Details anti-CDC26 Antibody

Target: CDC26 (Cell Division Cycle 26 Homolog (CDC26))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC26 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NIRKDLETRK KQKEDVEVVG GSDGEGAIGL SSDPKSREQM INDRIGYKPQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CDC26. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDC26

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 85 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDC26

Target: CDC26 (Cell Division Cycle 26 Homolog (CDC26))

Alternative Name: CDC26 (CDC26 Products)

Background: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc26, a component of cell cycle anaphase-promoting complex (APC). APC is composed of a group of highly conserved proteins and functions as a cell cycle-regulated ubiquitin-protein ligase. APC thus is responsible for the cell cycle regulated proteolysis of various proteins.
Alias Symbols: C9orf17, APC12, ANAPC12
Protein Interaction Partner: ANAPC2, CDC16, ANAPC4, CDC20, UBC, PHF8, SOX2, ANAPC15, ANAPC1, ANAPC13, CDC27, Gm9174, Anapc5, Mad2l1, Cdc23, Bub1b, APC2, CDH1,
Protein Size: 85

Molecular Weight: 10 kDa

Gene ID: 246184

NCBI Accession: NM_139286, NP_644815

UniProt: Q8NHZ8