RECK antibody (Middle Region)
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- Target See all RECK Antibodies
- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RECK antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SCIVGGKRKS HGTSFTIDCN VCSCFAGNLV CSTRLCLSEH SSDDDRRTFT
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Reck. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product RECK Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 971 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
- Alternative Name
- Reck (RECK Products)
- Synonyms
- ST15 antibody, St15 antibody, mRECK antibody, reversion inducing cysteine rich protein with kazal motifs antibody, reversion-inducing-cysteine-rich protein with kazal motifs antibody, RECK antibody, Reck antibody
- Background
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Reck negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. It appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Alias Symbols: MGC169689, St15, mRECK
Protein Size: 971 - Molecular Weight
- 104 kDa
- Gene ID
- 53614
- NCBI Accession
- NM_016678, NP_057887
- UniProt
- Q9Z0J1
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