NLRP5 antibody (N-Term)

Catalog No. ABIN2787916

Product Details anti-NLRP5 Antibody

Target: NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LAWATSISIF ENMNLRTLSE KARDDMKRHS PEDPEATMTD QGPSKEKVPG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against NLRP5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NLRP5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1200 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NLRP5

Target: NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))

Alternative Name: NLRP5 (NLRP5 Products)

Synonyms: CLR19.8 antibody, MATER antibody, NALP5 antibody, PAN11 antibody, PYPAF8 antibody, Mater antibody, Nalp5 antibody, Op1 antibody, NLR family pyrin domain containing 5 antibody, NLR family, pyrin domain containing 5 antibody, NLRP5 antibody, Nlrp5 antibody

Background: The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis.
Alias Symbols: CLR19.8, MATER, NALP5, PAN11, PYPAF8
Protein Interaction Partner: UBC,
Protein Size: 1200

Molecular Weight: 134 kDa

Gene ID: 126206

NCBI Accession: NM_153447, NP_703148

UniProt: P59047

Pathways: Inflammasome