DRAM antibody (N-Term)

Catalog No. ABIN2787866

Product Details anti-DRAM Antibody

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRAM antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TMYTRYKIVQ KQNQTCYFST PVFNLVSLVL GLVGCFGMGI VANFQELAVP

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against DRAM. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DRAM

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 238 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DRAM

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Alternative Name: DRAM (DRAM1 Products)

Synonyms: DRAM1 antibody, DRAM antibody, 1200002N14Rik antibody, Dram antibody, dram antibody, DNA damage regulated autophagy modulator 1 antibody, DNA-damage regulated autophagy modulator 1 antibody, DNA damage regulated autophagy modulator 1 L homeolog antibody, DRAM1 antibody, Dram1 antibody, dram1.L antibody

Background: This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.
Alias Symbols: DRAM, FLJ11259
Protein Interaction Partner: C1orf21, APP,
Protein Size: 238

Molecular Weight: 26 kDa

Gene ID: 55332

NCBI Accession: NM_018370, NP_060840

UniProt: Q8N682