EIF2C3 antibody (N-Term)

Catalog No. ABIN504548

Product Details anti-EIF2C3 Antibody

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Cow, Zebrafish (Danio rerio), Rat, Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2C3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MCEVLDIHNI DEQPRPLTDS HRVKFTKEIK GLKVEVTHCG TMRRKYRVCN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against EIF2C3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EIF2C3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 626 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EIF2C3

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Alternative Name: EIF2C3 (EIF2C3 Products)

Background: EIF2C3 is a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is
Alias Symbols: AGO3, FLJ12765, MGC86946, EIF2C3
Protein Interaction Partner: AGO4, TNRC6C, TNRC6A, AGO2, AGO1, ZNF346, DICER1, TNRC6B, TARBP2, PRKAR1A, ATP6V0D2, UBC, SLC22A2, BDNF, ATP4B, CAND1, CUL3, CUL5, AGO3, ATAD3B, WDR77, PSPC1, QPCTL, OTUD4, SF3B6, EIF3L, PRPF31, SUN2, PHB2, STK38, SPIN1, RUVBL2, IPO8, TAB1, PRMT5, TUBB4B,
Protein Size: 626

Molecular Weight: 69 kDa

Gene ID: 192669

NCBI Accession: NM_177422, NP_803171

UniProt: B1ALI0

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway