TSTA3 antibody (N-Term)

Catalog No. ABIN2787788

Product Details anti-TSTA3 Antibody

Target: TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSTA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MGEPQGSMRI LVTGGSGLVG KAIQKVVADG AGLPGEDWVF VSSKDADLTD

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TSTA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TSTA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 321 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TSTA3

Target: TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))

Alternative Name: TSTA3 (TSTA3 Products)

Synonyms: FX antibody, P35B antibody, SDR4E1 antibody, AI256181 antibody, Tstap35b antibody, p35b antibody, sdr4e1 antibody, TSTA3 antibody, zgc:101805 antibody, si:dkey-235d18none antibody, Fx antibody, tissue specific transplantation antigen P35B antibody, tissue specific transplantation antigen P35B L homeolog antibody, TSTA3 antibody, Tsta3 antibody, tsta3 antibody, tsta3.L antibody

Background: Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
Alias Symbols: FX, P35B, SDR4E1
Protein Interaction Partner: UBC, COASY, EFHD2, PPME1, GLRX3, GMPS, RCN1, RBBP7, BAG3, RIOK2, ID2, DNAJC9, DSTN, NEDD4,
Protein Size: 321

Molecular Weight: 35 kDa

Gene ID: 7264

NCBI Accession: NM_003313, NP_003304

UniProt: Q13630