EFHD2 antibody (N-Term)

Catalog No. ABIN2787767

Product Details anti-EFHD2 Antibody

Target: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Pig, Cow, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EFHD2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MGTPGEGLGR CSHALIRGVP ESLASGEGAG AGLPALDLAK AQREHGVLGG

Predicted Reactivity: Cow: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rat: 93%, Yeast: 83%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against EFHD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EFHD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 240 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EFHD2

Target: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Alternative Name: EFHD2 (EFHD2 Products)

Synonyms: SWS1 antibody, efhd2 antibody, EFHD2 antibody, MGC131292 antibody, 2600015J22Rik antibody, AA408606 antibody, D4Wsu27e antibody, si:dkey-72l14.9 antibody, wu:fb80e07 antibody, EF-hand domain family member D2 antibody, EF-hand domain family, member D2 antibody, EF-hand domain family member D2 L homeolog antibody, EF hand domain containing 2 antibody, EFHD2 antibody, Efhd2 antibody, efhd2 antibody, efhd2.L antibody

Background: EFHD2 may regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. It plays a role as negative regulator of the canonical NF-kappa-B-activating branch. EFHD2 controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Alias Symbols: MGC4342, RP3-467K16.3, SWS1
Protein Interaction Partner: UBC, COASY, CHMP4A, GLRX3, GMPS, TSTA3, RCN1, PTPN11, IDH1, ENO2, DCK, FBXO6, PAN2, APP, LRRK2, ELAVL1,
Protein Size: 240

Molecular Weight: 26 kDa

Gene ID: 79180

NCBI Accession: NM_024329, NP_077305

UniProt: Q96C19