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GPX4 antibody (Middle Region)

GPX4 Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Guinea Pig, Cow, Goat, Saccharomyces cerevisiae WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787700
  • Target See all GPX4 Antibodies
    GPX4 (Glutathione Peroxidase 4 (GPX4))
    Binding Specificity
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Zebrafish (Danio rerio), Guinea Pig, Cow, Goat, Saccharomyces cerevisiae
    Host
    • 51
    • 4
    • 1
    Rabbit
    Clonality
    • 43
    • 13
    Polyclonal
    Conjugate
    • 24
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GPX4 antibody is un-conjugated
    Application
    • 33
    • 18
    • 16
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    QUGKTEVNYT QLVDLHARYA ECGLRILAFP CNQFGKQEPG SNEEIKEFAA
    Predicted Reactivity
    Cow: 86%, Goat: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Rat: 86%, Yeast: 93%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against GPX4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human GPX4
    Top Product
    Discover our top product GPX4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 197 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    GPX4 (Glutathione Peroxidase 4 (GPX4))
    Alternative Name
    GPX4 (GPX4 Products)
    Synonyms
    GPx-4 antibody, GSHPx-4 antibody, MCSP antibody, PHGPx antibody, snGPx antibody, snPHGPx antibody, Phgpx antibody, gpx-4 antibody, snGpx antibody, cb563 antibody, cb691 antibody, PHGPxa antibody, sb:cb563 antibody, zgc:92253 antibody, wu:fb82e03 antibody, 1700027O09Rik antibody, mtPHGPx antibody, ATGPX4 antibody, F11L15.5 antibody, glutathione peroxidase 4 antibody, GP-GPx4 antibody, glutathione peroxidase 4 antibody, glutathione peroxidase 4a antibody, GPX4 antibody, Gpx4 antibody, gpx4a antibody
    Background
    Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists, alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists, alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.
    Alias Symbols: MCSP, PHGPx, snGPx, snPHGPx
    Protein Interaction Partner: UBC, PRDX6, MAPK13, OTUD5,
    Protein Size: 197
    Molecular Weight
    22 kDa
    Gene ID
    2879
    NCBI Accession
    NM_002085, NP_002076
    UniProt
    P36969
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