CPE antibody (N-Term)

Catalog No. ABIN2787685

Product Details anti-CPE Antibody

Target: CPE (Carboxypeptidase E (CPE))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GMRRRRRLQQ EDGISFEYHR YPELREALVS VWLQCTAISR IYTVGRSFEG

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against CPE. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CPE

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 476 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CPE

Target: CPE (Carboxypeptidase E (CPE))

Alternative Name: CPE (CPE Products)

Synonyms: CPE antibody, CPH antibody, Cph-1 antibody, Cph1 antibody, R74677 antibody, fat antibody, CARBE antibody, Cph antibody, si:ch211-198g9.2 antibody, zgc:85981 antibody, carboxypeptidase E antibody, carboxypeptidase E L homeolog antibody, CPE antibody, cpe antibody, Cpe antibody, cpe.L antibody

Background: CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteinsThis gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: PRKAA1, UBC, LRIF1, POLDIP2, MED31, ROBO2, POLA2, CHD3, TRH, NTS, GTF3C1, UTP14A, RPA1, PMCH, INS, GCG, GAST, CCK, BDNF,
Protein Size: 476

Molecular Weight: 52 kDa

Gene ID: 1363

NCBI Accession: NM_001873, NP_001864

UniProt: P16870

Pathways: Peptide Hormone Metabolism, Synaptic Membrane