ERCC4 antibody (Middle Region)
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- Target See all ERCC4 Antibodies
- ERCC4 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Rat, Dog, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ERCC4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- FLLRLYRKTF EKDSKAEEVW MKFRKEDSSK RIRKSHKRPK DPQNKERAST
- Predicted Reactivity
- Dog: 83%, Horse: 85%, Human: 100%, Rat: 85%
- Characteristics
- This is a rabbit polyclonal antibody against ERCC4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ERCC4
- Top Product
- Discover our top product ERCC4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 916 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ERCC4 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4))
- Alternative Name
- ERCC4 (ERCC4 Products)
- Synonyms
- ERCC11 antibody, FANCQ antibody, RAD1 antibody, XPF antibody, AI606920 antibody, Xpf antibody, RGD1560340 antibody, fi03a05 antibody, zgc:63468 antibody, wu:fi03a05 antibody, ercc11 antibody, rad1 antibody, xpf antibody, ERCC4 antibody, LOC100231158 antibody, ERCC excision repair 4, endonuclease catalytic subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 4 antibody, excision repair cross-complementation group 4 antibody, excision repair cross-complementation group 4 L homeolog antibody, ERCC4 antibody, Ercc4 antibody, ercc4 antibody, ercc4.L antibody, XPF antibody
- Background
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The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause
Alias Symbols: RAD1, XPF, ERCC11
Protein Interaction Partner: vpr, SLX4, UBC, MSH2, ERCC1, ALYREF, VPS26A, UBE2B, SLX1A, POLR2A, SUMO2, GTF2H1, SPTAN1, ERCC6, TADA2A, FANCG, PLK1, SLX4IP, SLX1B, RAD52, SPTA1, FANCA,
Protein Size: 916 - Molecular Weight
- 101 kDa
- Gene ID
- 2072
- NCBI Accession
- NM_005236, NP_005227
- UniProt
- Q92889
- Pathways
- DNA Damage Repair
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