DUSP5 antibody (Middle Region)
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- Target See all DUSP5 Antibodies
- DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DUSP5 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- AGSSLIGHLQ TLSPDMQGAY CTFPASVLAP VPTHSTVSEL SRSPVATATS
- Predicted Reactivity
- Cow: 85%, Dog: 92%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 79%
- Characteristics
- This is a rabbit polyclonal antibody against DUSP5. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human DUSP5
- Top Product
- Discover our top product DUSP5 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 384 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))
- Alternative Name
- DUSP5 (DUSP5 Products)
- Synonyms
- DUSP5 antibody, wu:fc03b11 antibody, wu:fc86e02 antibody, MGC84792 antibody, dusp antibody, hvh3 antibody, DUSP antibody, HVH3 antibody, Cpg21 antibody, Gm337 antibody, dual specificity phosphatase 5 antibody, dual specificity phosphatase 5 S homeolog antibody, DUSP5 antibody, dusp5 antibody, dusp5.S antibody, Dusp5 antibody
- Background
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The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
Alias Symbols: DUSP, HVH3
Protein Interaction Partner: ELAVL1, UBC, MAPK3, MAPK1,
Protein Size: 384 - Molecular Weight
- 42 kDa
- Gene ID
- 1847
- NCBI Accession
- NM_004419, NP_004410
- UniProt
- Q16690
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