TRIM15 antibody (Middle Region)

Catalog No. ABIN406662

Product Details anti-TRIM15 Antibody

Target: TRIM15 (Tripartite Motif Containing 15 (TRIM15))

Binding Specificity: Middle Region

Reactivity: Human, Cow, Rabbit, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM15 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: HLEIDSGVIT LDPQTASRSL VLSEDRKSVR YTRQKKSLPD SPLRFDGLPA

Predicted Reactivity: Cow: 86%, Human: 100%, Pig: 86%, Rabbit: 79%, Yeast: 100%

Characteristics: This is a rabbit polyclonal antibody against TRIM15. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM15

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 465 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TRIM15 antibody (ABIN406662)

Uchil, Quinlan, Chan, Luna, Mothes: "TRIM E3 ligases interfere with early and late stages of the retroviral life cycle." in: PLoS pathogens, Vol. 4, Issue 2, pp. e16, (2008) (PubMed).

Target Details for TRIM15

Target: TRIM15 (Tripartite Motif Containing 15 (TRIM15))

Alternative Name: TRIM15 (TRIM15 Products)

Background: TRIM15 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Its function has not been identified. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Alias Symbols: RNF93, ZNF178, ZNFB7
Protein Interaction Partner: FAM151B, FAM161A, RABGEF1, TRIM8, TINF2, ACD, TRIM15, EHMT1, TAF9B, SNW1, MED7, MYBL2, IRF5, GTF2E1, UBE2U,
Protein Size: 465

Molecular Weight: 52 kDa

Gene ID: 89870

NCBI Accession: NM_033229, NP_150232

UniProt: Q9C019