TFEB antibody (Middle Region)

Catalog No. ABIN2787554

Product Details anti-TFEB Antibody

Target: TFEB (Transcription Factor EB (TFEB))

Binding Specificity: Middle Region

Reactivity: Human, Cow, Dog, Horse, Goat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFEB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DFSHSLSFGG REDEGPPGYP EPLAPGHGSP FPSLSKKDLD LMLLDDSLLP

Predicted Reactivity: Cow: 79%, Dog: 86%, Goat: 79%, Horse: 85%, Human: 100%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against TFEB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TFEB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 476 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TFEB

Target: TFEB (Transcription Factor EB (TFEB))

Alternative Name: TFEB (TFEB Products)

Background: The TFEB gene fuses with an intronless gene in renal tumors harboring the t(6,11)(p21,q13) chromosome translocation. It encodes a protein that is a highly sensitive and specific diagnostic marker for renal neoplasms.
Alias Symbols: AlphaTFEB, TCFEB, BHLHE35, ALPHATFEB
Protein Interaction Partner: SRPK1, YWHAQ, TFEC, TFE3, MITF,
Protein Size: 476

Molecular Weight: 53 kDa

Gene ID: 7942

NCBI Accession: NM_007162, NP_009093

UniProt: P19484