GCFC2 antibody (N-Term)

Catalog No. ABIN2787542

Product Details anti-GCFC2 Antibody

Target: GCFC2 (GC-Rich Sequence DNA-Binding Factor 2 (GCFC2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCFC2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SEPDDHEKRI PFTLRPQTLR QRMAEESISR NEETSEESQE DEKQDTWEQQ

Predicted Reactivity: Cow: 79%, Dog: 100%, Guinea Pig: 92%, Horse: 85%, Human: 100%, Mouse: 85%, Rabbit: 83%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against C2orf3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C2orf3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 781 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GCFC2

Target: GCFC2 (GC-Rich Sequence DNA-Binding Factor 2 (GCFC2))

Alternative Name: C2orf3 (GCFC2 Products)

Synonyms: C2orf3 antibody, DNABF antibody, GCF antibody, TCF9 antibody, A130099G21 antibody, AW146020 antibody, GCF2 antibody, Tcf9 antibody, C11H2orf3 antibody, RGD1304792 antibody, C17H2orf3 antibody, zgc:171819 antibody, GC-rich sequence DNA-binding factor 2 antibody, GC-rich sequence DNA binding factor 2 antibody, GCFC2 antibody, Gcfc2 antibody, gcfc2 antibody

Background: The first mRNA transcript isolated for C2orf3 gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). C2orf3 belongs to the GCF family. It is a factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene.
Alias Symbols: DNABF, GCF, TCF9, C2orf3
Protein Interaction Partner: HDAC11, CREB3L2, ATXN1, SUMO2,
Protein Size: 781

Molecular Weight: 89 kDa

Gene ID: 6936

NCBI Accession: NM_003203, NP_003194

UniProt: P16383