POU2F3 antibody (C-Term)

Catalog No. ABIN2787499

Product Details anti-POU2F3 Antibody

Target: POU2F3 (POU Class 2 Homeobox 3 (POU2F3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Sheep, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU2F3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LSVPPVHSTM PGTVTSSCSP GNNSRPSSPG SGLHASSPTA SQNNSKAAVN

Predicted Reactivity: Cow: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against POU2F3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human POU2F3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for POU2F3

Target: POU2F3 (POU Class 2 Homeobox 3 (POU2F3))

Alternative Name: POU2F3 (POU2F3 Products)

Background: This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: PLA1, OCT11, PLA-1, Epoc-1, OCT-11, OTF-11, Skn-1a
Protein Size: 221

Molecular Weight: 24 kDa

Gene ID: 25833

NCBI Accession: NM_001244682, NP_001231611

UniProt: Q9UKI9