PREB antibody (N-Term)

Catalog No. ABIN2787462

Product Details anti-PREB Antibody

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Pig, Rabbit, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PREB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RRRGVELYRA PFPLYALRID PKTGLLIAAG GGGAAKTGIK NGVHFLQLEL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Preb. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Preb

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 417 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PREB

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Alternative Name: Preb (PREB Products)

Synonyms: C85705 antibody, SEC12 antibody, prolactin regulatory element binding antibody, PREB antibody, Preb antibody

Background: Preb was first identified based on its probable role in the regulation of pituitary gene transcription. It binds to the prolactin gene (PRL) promoter and seems to activate transcription. Guanine nucleotide exchange factor that activates SARA2. It is also required for the formation of COPII transport vesicles from the ER.
Alias Symbols: C85705
Protein Interaction Partner: PREB, Ssbp4, Trip13, TGFBR1,
Protein Size: 417

Molecular Weight: 45 kDa

Gene ID: 50907

NCBI Accession: NM_016703, NP_057912

UniProt: Q9WUQ2

Pathways: ER-Nucleus Signaling