TCF7L1 antibody (N-Term)
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- Target See all TCF7L1 Antibodies
- TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TCF7L1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ESENQSSSSD SEAERRPQPV RDTFQKPRDY FAEVRRPQDS AFFKGPPYPG
- Predicted Reactivity
- Cow: 86%, Dog: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against TCF7L1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L1
- Top Product
- Discover our top product TCF7L1 Primary Antibody
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anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (N-Term) antibody
TCF7L1 Reactivity: Human WB, ChIP-seq, ChIP, CUT&RUN Host: Rabbit Polyclonal unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (Internal Region) antibodyTCF7L1 Reactivity: Human, Mouse, Rat WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (AA 35-84) antibodyTCF7L1 Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (AA 489-586) antibodyTCF7L1 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (AA 80-99) antibodyTCF7L1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (AA 70-98), (N-Term) antibodyTCF7L1 Reactivity: Human WB Host: Rabbit Polyclonal RB43616 unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (AA 72-121) antibodyTCF7L1 Reactivity: Human, Mouse, Rabbit WB Host: Rabbit Polyclonal unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (AA 561-588), (C-Term) antibodyTCF7L1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (N-Term) antibodyTCF7L1 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 588 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))
- Alternative Name
- TCF7L1 (TCF7L1 Products)
- Background
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TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
Alias Symbols: TCF-3, TCF3
Protein Interaction Partner: UBC, mdfic, Mdfi, DAZAP2, CTNNB1,
Protein Size: 588 - Molecular Weight
- 63 kDa
- Gene ID
- 83439
- NCBI Accession
- NM_031283, NP_112573
- UniProt
- Q9HCS4
- Pathways
- WNT Signaling, Stem Cell Maintenance
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