FEV antibody (N-Term)

Catalog No. ABIN2787444

Product Details anti-FEV Antibody

Target: FEV (FEV (ETS Oncogene Family) (FEV))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Cow, Guinea Pig, Rat, Rabbit, Zebrafish (Danio rerio), Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEV antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PLSPAVQKGS GQIQLWQFLL ELLADRANAG CIAWEGGHGE FKLTDPDEVA

Predicted Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against FEV. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FEV

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 238 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FEV

Target: FEV (FEV (ETS Oncogene Family) (FEV))

Alternative Name: FEV (FEV Products)

Synonyms: FEV antibody, HSRNAFEV antibody, PET-1 antibody, Pet-1 antibody, Pet1 antibody, mPet-1 antibody, pet1 antibody, zgc:158720 antibody, FEV, ETS transcription factor antibody, FEV (ETS oncogene family) antibody, FEV antibody, Fev antibody, fev antibody

Background: This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.
Alias Symbols: HSRNAFEV, PET-1
Protein Interaction Partner: UBC,
Protein Size: 238

Molecular Weight: 25 kDa

Gene ID: 54738

NCBI Accession: NM_017521, NP_059991

UniProt: Q99581