PYCR1 antibody (Middle Region)

Catalog No. ABIN2787369

Product Details anti-PYCR1 Antibody

Target: PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PYCR1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KMLLHSEQHP GQLKDNVSSP GGATIHALHV LESGGFRSLL INAVEASCIR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PYCR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PYCR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 316 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PYCR1

Target: PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

Alternative Name: PYCR1 (PYCR1 Products)

Background: This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes
Alias Symbols: P5C, P5CR, PIG45, PP222, PYCR, PRO3, ARCL2B, ARCL3B
Protein Interaction Partner: FUS, SUMO2, NEDD8, MDM2, SUZ12, RNF2, BMI1, HNRNPD, BAG3, BNIPL, UBC, ITGA4, DAB2, MDC1, CUL3, NUDT21, CDK2AP2,
Protein Size: 316

Molecular Weight: 33 kDa

Gene ID: 5831

NCBI Accession: NM_153824, NP_722546

UniProt: A6NFM2