PYCR1 antibody (Middle Region)

Catalog No. ABIN2787369

Product Details anti-PYCR1 Antibody

Target: PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PYCR1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KMLLHSEQHP GQLKDNVSSP GGATIHALHV LESGGFRSLL INAVEASCIR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PYCR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PYCR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 316 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PYCR1

Target: PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

Alternative Name: PYCR1 (PYCR1 Products)

Synonyms: arcl2b antibody, p5c antibody, p5cr antibody, pig45 antibody, pp222 antibody, pro3 antibody, pycr antibody, ARCL2B antibody, ARCL3B antibody, P5C antibody, P5CR antibody, PIG45 antibody, PP222 antibody, PRO3 antibody, PYCR antibody, zgc:73112 antibody, pyrroline-5-carboxylate reductase family, member 1 L homeolog antibody, pyrroline-5-carboxylate reductase 1 antibody, pyrroline-5-carboxylate reductase 1a antibody, pycr1.L antibody, PYCR1 antibody, Pycr1 antibody, pycr1a antibody

Background: This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes
Alias Symbols: P5C, P5CR, PIG45, PP222, PYCR, PRO3, ARCL2B, ARCL3B
Protein Interaction Partner: FUS, SUMO2, NEDD8, MDM2, SUZ12, RNF2, BMI1, HNRNPD, BAG3, BNIPL, UBC, ITGA4, DAB2, MDC1, CUL3, NUDT21, CDK2AP2,
Protein Size: 316

Molecular Weight: 33 kDa

Gene ID: 5831

NCBI Accession: NM_153824, NP_722546

UniProt: A6NFM2