PSMA3 antibody (Middle Region)
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- Target See all PSMA3 Antibodies
- PSMA3 (Proteasome Subunit Alpha Type 3 (PSMA3))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Cow, Rabbit, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMA3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TCRDIVKEVA KIIYIVHDEV KDKAFELELS WVGELTNGRH EIVPKDIREE
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 92%, Yeast: 77%, Zebrafish: 77%
- Characteristics
- This is a rabbit polyclonal antibody against PSMA3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PSMA3
- Top Product
- Discover our top product PSMA3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 248 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PSMA3 (Proteasome Subunit Alpha Type 3 (PSMA3))
- Alternative Name
- PSMA3 (PSMA3 Products)
- Synonyms
- HC8 antibody, PSC3 antibody, Psma3l antibody, psma3 antibody, im:6909944 antibody, zgc:114044 antibody, Lmpc8 antibody, proteasome subunit alpha 3 antibody, proteasome subunit alpha 3 L homeolog antibody, proteasome (prosome, macropain) subunit, alpha type 3 antibody, PSMA3 antibody, Psma3 antibody, psma3.L antibody, psma3 antibody
- Background
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA3 is a member of the peptidase T1A family, that is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
Alias Symbols: HC8, MGC12306, MGC32631, PSC3
Protein Interaction Partner: SF1, STX4, SNRPC, SNRPB, RAB3IL1, PSMB4, PSMA6, PSMA3, PSMA1, NPPB, CTAGE5, LETM1, LASP1, KRAS, NPBWR2, GATA3, GATA2, CYBA, CST2, CDK6, ATP6V0C, DMC1, SLMO1, BTN2A2, STX6, SERF2, HUWE1, APLN, C1QTNF9B-AS1, C9orf106, KRTAP26-1, KRTAP19-5, KRTAP8-1, RTP5, R
Protein Size: 248 - Molecular Weight
- 28 kDa
- Gene ID
- 5684
- NCBI Accession
- NM_152132, NP_687033
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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