MAPK7 antibody (Middle Region)
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- Target See all MAPK7 Antibodies
- MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAPK7 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- FDMGVADGPQ DGQADSASLS ASLLADWLEG HGMNPADIES LQREIQMDSP
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against MAPK7. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MAPK7
- Top Product
- Discover our top product MAPK7 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 816 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
- Alternative Name
- MAPK7 (MAPK7 Products)
- Synonyms
- BMK1 antibody, ERK4 antibody, ERK5 antibody, PRKM7 antibody, Erk5-T antibody, ATMPK7 antibody, F8D23.5 antibody, F8D23_5 antibody, MAP kinase 7 antibody, Bmk1 antibody, Erk5 antibody, Prkm7 antibody, ERK-5 antibody, bmk1 antibody, erk4 antibody, mapk7 antibody, prkm7 antibody, mitogen-activated protein kinase 7 antibody, MAP kinase 7 antibody, mitogen-activated protein kinase 7 L homeolog antibody, MAPK7 antibody, Mapk7 antibody, MPK7 antibody, mapk7.L antibody
- Background
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.
Alias Symbols: BMK1, ERK4, ERK5, PRKM7
Protein Interaction Partner: PRKCZ, NFE2L2, UBE2C, MAP3K2, TP53, MAP2K5, PML, DSG1, DSC1, PFDN6, VBP1, MAPK7, PFDN5, PFDN4, PFDN2, PFDN1, JUP, GAPDH, BAG3, PKM, LDHC, HSP90AB1, HSPA5, HSPA4, ATP5A1, ACTB, PPP3CA, TUBB, MYLK2, GANAB, CDC37, YWHAZ, YWHAH, YWHAG, YWHAE, UBC, HSP90B1, FS
Protein Size: 816 - Molecular Weight
- 88 kDa
- Gene ID
- 5598
- NCBI Accession
- NM_139034, NP_620603
- UniProt
- Q13164
- Pathways
- MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
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