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CARD9 antibody (Middle Region)

CARD9 Reactivity: Human, Mouse, Horse, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787348
  • Target See all CARD9 Antibodies
    CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))
    Binding Specificity
    • 15
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 40
    • 3
    • 3
    • 2
    • 1
    Human, Mouse, Horse, Dog
    Host
    • 38
    • 3
    Rabbit
    Clonality
    • 40
    • 1
    Polyclonal
    Conjugate
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CARD9 antibody is un-conjugated
    Application
    • 34
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    ALHQEQVLRN PHDAGLSSGE PPEKERRRLK ESFENYRRKR ALRKMQKGWR
    Predicted Reactivity
    Dog: 92%, Horse: 86%, Human: 100%, Mouse: 90%
    Characteristics
    This is a rabbit polyclonal antibody against CARD9. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human CARD9
    Top Product
    Discover our top product CARD9 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 536 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))
    Alternative Name
    CARD9 (CARD9 Products)
    Synonyms
    Gm782 antibody, card9 antibody, CANDF2 antibody, hCARD9 antibody, caspase recruitment domain family, member 9 antibody, caspase recruitment domain family member 9 antibody, Card9 antibody, CARD9 antibody, card9 antibody
    Background
    The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.
    Alias Symbols: hCARD9, CANDF2
    Protein Interaction Partner: KRTAP10-3, MFAP1, MEOX2, LMO1, ABLIM1, KRT31, KRT19, PHC2, DAXX, TRIM23, AES, KRTAP10-5, KRTAP10-1, CCDC36, TRIM42, CEP57L1, RTP5, PPP1R18, TCEANC, ALS2CR11, ZNF417, CWF19L2, ZNF572, KRT40, SSX2IP, PNMA5, C1orf94, ZNF587, LZTS2, ZCCHC7, FAM161A, CEP70, FA
    Protein Size: 536
    Molecular Weight
    62 kDa
    Gene ID
    64170
    NCBI Accession
    NM_052813, NP_434700
    UniProt
    Q9H257
    Pathways
    Activation of Innate immune Response
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