POLR2C antibody (C-Term)

Catalog No. ABIN2787341

Product Details anti-POLR2C Antibody

Target: POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Horse, Cow, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR2C antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YDPDNALRHT VYPKPEEWPK SEYSELDEDE SQAPYDPNGK PERLGDLGPR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Polr2c. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of mouse POLR2C

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for POLR2C

Target: POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))

Alternative Name: Polr2c (POLR2C Products)

Background: This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21.
Alias Symbols: RPB3, RPB31, hRPB33, hsRPB3
Protein Size: 332

Molecular Weight: 36 kDa

Gene ID: 5432

NCBI Accession: NM_032940, NP_116558

UniProt: P19387

Pathways: Regulatory RNA Pathways