PLSCR1 antibody (N-Term)

Catalog No. ABIN2787256

Product Details anti-PLSCR1 Antibody

Target: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Binding Specificity: N-Term

Reactivity: Human, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLSCR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MDKQNSQMNA SHPETNLPVG YPPQYPPTAF QGPPGYSGYP GPQVSYPPPP

Predicted Reactivity: Dog: 85%, Human: 100%, Rabbit: 77%

Characteristics: This is a rabbit polyclonal antibody against PLSCR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PLSCR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 318 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLSCR1

Target: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Alternative Name: PLSCR1 (PLSCR1 Products)

Synonyms: mmtra1b antibody, MGC84969 antibody, PLSCR1 antibody, MGC148322 antibody, MMTRA1B antibody, MmTRA1a antibody, MmTRA1b antibody, Nor1 antibody, Tra1 antibody, Tra1a antibody, Tra1b antibody, Tras1 antibody, Tras2 antibody, PLSCR2 antibody, phospholipid scramblase 1 L homeolog antibody, phospholipid scramblase 1 antibody, plscr1.L antibody, PLS1 antibody, PVX_111580 antibody, PLSCR1 antibody, plscr1 antibody, Plscr1 antibody, LOC100712949 antibody, PLSCR2 antibody, LOC100341366 antibody, LOC611500 antibody

Background: PLSCR1 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.PLSCR1 may play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
Alias Symbols: MMTRA1B
Protein Interaction Partner: PKD2, P2RY6, ILF3, EWSR1, ESR2, DOCK2, CTSZ, CATSPER1, LONRF1, KRTAP4-2, ZNF587, LINC01547, KRTAP9-2, GDPD5, SCNM1, DMRT3, VPS37C, PRR13, DEF6, LGALS9C, KRTAP4-11, KRTAP5-6, KRTAP10-3, KRTAP10-11, KRTAP10-9, LCE3C, LCE2D, TRIM42, BCL6B, LCE4A, ZNF417, MGA
Protein Size: 318

Molecular Weight: 35 kDa

Gene ID: 5359

NCBI Accession: NM_021105, NP_066928

UniProt: O15162

Pathways: Cellular Response to Molecule of Bacterial Origin