BCL7A antibody (Middle Region)

Catalog No. ABIN2787251

Product Details anti-BCL7A Antibody

Target: BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL7A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CGSEVTTPEN SSSPGMMDMH DDNSNQSSIA DASPIKQENS SNSSPAPEPN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against BCL7A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BCL7A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 231 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BCL7A

Target: BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))

Alternative Name: BCL7A (BCL7A Products)

Synonyms: BCL7 antibody, cb585 antibody, id:ibd1097 antibody, sb:cb585 antibody, wu:fk02d01 antibody, zgc:92023 antibody, 4432415N06Rik antibody, AI448316 antibody, bcl7a antibody, MGC89576 antibody, BCL7A antibody, BCL tumor suppressor 7A antibody, B-cell CLL/lymphoma 7A antibody, B cell CLL/lymphoma 7A antibody, B-cell CLL/lymphoma 7A L homeolog antibody, BCL7A antibody, bcl7a antibody, Bcl7a antibody, bcl7a.L antibody

Background: This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: BCL7
Protein Interaction Partner: ALAS1, UBC, CBX5, CUL3, Bcl7b, SMARCA4, SMARCA2, RELB,
Protein Size: 231

Molecular Weight: 25 kDa

Gene ID: 605

NCBI Accession: NM_020993, NP_066273

UniProt: Q4VC05