RAB22A antibody (Middle Region)

Catalog No. ABIN2787223

Product Details anti-RAB22A Antibody

Target: RAB22A (RAB22A, Member RAS Oncogene Family (RAB22A))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Pig, Rabbit, Cow, Zebrafish (Danio rerio), Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB22A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: IFVETSAKNA ININELFIEI SRRIPSTDAN LPSGGKGFKL RRQPSEPKRS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RAB22A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAB22A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 194 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-RAB22A antibody (ABIN2787223)

Cebrian, Croce, Guerrero, Blanchard, Mayorga: "Rab22a controls MHC-I intracellular trafficking and antigen cross-presentation by dendritic cells." in: EMBO reports, Vol. 17, Issue 12, pp. 1753-1765, (2016) (PubMed).

Target Details for RAB22A

Target: RAB22A (RAB22A, Member RAS Oncogene Family (RAB22A))

Alternative Name: RAB22A (RAB22A Products)

Background: The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between endosom
Alias Symbols: MGC16770
Protein Interaction Partner: APPL2, UBC, ATP6V1B1, RBSN, RAB3GAP1, RABGEF1, RAB5A, ELAVL1, SMURF2, EEA1, RABAC1, RAB7A,
Protein Size: 194

Molecular Weight: 22 kDa

Gene ID: 57403

NCBI Accession: NM_020673, NP_065724

UniProt: P35285