ACTR3B antibody (N-Term)

Catalog No. ABIN2787218

Product Details anti-ACTR3B Antibody

Target: ACTR3B (ARP3 Actin-Related Protein 3 Homolog B (ACTR3B))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Zebrafish (Danio rerio), Cow, Dog, Rabbit, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTR3B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAGSLPPCVV DCGTGYTKLG YAGNTEPQFI IPSCIAIRES AKVVDQAQRR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ACTR3B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACTR3B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 418 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACTR3B

Target: ACTR3B (ARP3 Actin-Related Protein 3 Homolog B (ACTR3B))

Alternative Name: ACTR3B (ACTR3B Products)

Synonyms: RGD1565759 antibody, ARP11 antibody, ARP3BETA antibody, 9630005C02 antibody, AW047569 antibody, Arp3b antibody, Arp3beta antibody, ARP3 actin related protein 3 homolog B antibody, ARP3 actin-related protein 3B antibody, Actr3b antibody, ACTR3B antibody

Background: ACTR3B plays a role in the organization of the actin cytoskeleton.ACTR3B may function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. ACTR3B may decrease the metastatic potential of tumors.
Alias Symbols: ARP11, ARP3BETA, DKFZp686O24114
Protein Interaction Partner: PAN2, EXOC5, UBC, RSRC1, ARPC3P1, ARPC5L, CCAR2, TWF2, ARPC1A, ARPC2, ACTR2, ARPC1B, ARPC3, ARPC4, ARPC5, CDK4,
Protein Size: 418

Molecular Weight: 47 kDa

Gene ID: 57180

NCBI Accession: NM_020445, NP_065178

UniProt: Q9P1U1

Pathways: Regulation of Actin Filament Polymerization