EXOC6 antibody (N-Term)

Catalog No. ABIN2787171

Product Details anti-EXOC6 Antibody

Target: EXOC6 (Exocyst Complex Component 6 (EXOC6))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOC6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MLEEETDQTY ENVLAEIQSF ELPVEATLRS VYDDQPNAHK KFMEKLDACI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against EXOC6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EXOC6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 799 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EXOC6

Target: EXOC6 (Exocyst Complex Component 6 (EXOC6))

Alternative Name: EXOC6 (EXOC6 Products)

Background: The product of this gene belongs to the SEC15 family. It is highly similar to the protein encoded by Saccharomyces cerevisiae SEC15 gene. This protein is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DKFZp761I2124, EXOC6A, FLJ1125, FLJ11251, MGC33397, SEC15L, SEC15L1, SEC15L3, Sec15p, SEC15
Protein Interaction Partner: EGFR, UBC, ALB, RNF32, LOXL4, EXOC2, EXOC6, ECSIT, EXOSC1, MAST1, EXOC3, PRDX2, PSEN2, NOS3, GCDH, CYP2C8, APP, MYO5A,
Protein Size: 799

Molecular Weight: 88 kDa

Gene ID: 54536

NCBI Accession: NM_001013848, NP_001013870

UniProt: B3KXY5

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis