CENPN antibody (Middle Region)

Catalog No. ABIN2787136

Product Details anti-CENPN Antibody

Target: CENPN (Centromere Protein N (CENPN))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPN antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: SFKKILQRAL KNVTVSFRET EENAVWIRIA WGTQYTKPNQ YKPTYVVYYS

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against CENPN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CENPN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 353 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CENPN

Target: CENPN (Centromere Protein N (CENPN))

Alternative Name: CENPN (CENPN Products)

Background: The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPN is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).
Alias Symbols: BM039, C16orf60, CENP-N, FLJ13607, FLJ22660
Protein Interaction Partner: UBC, CENPP, CENPL, CENPU, CENPO, CENPM, CENPH, CENPK, CENPN, CENPQ, CENPI, CENPA,
Protein Size: 353

Molecular Weight: 41 kDa

Gene ID: 55839

NCBI Accession: NM_001100625, NP_001094095