ELP2 antibody (Middle Region)

Catalog No. ABIN2787102

Product Details anti-ELP2 Antibody

Target: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EESGVWLEQV RVGEVGGNTL GFYDCQFNED GSMIIAHAFH GALHLWKQNT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against ELP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ELP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 826 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ELP2

Target: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Alternative Name: ELP2 (ELP2 Products)

Synonyms: zgc:153559 antibody, SHINC-2 antibody, STATIP1 antibody, StIP antibody, AU023723 antibody, Epl2 antibody, StIP1 antibody, Statip1 antibody, F14J22.24 antibody, elongator protein 2 antibody, elongator acetyltransferase complex subunit 2 antibody, elongator protein 2 antibody, elp2 antibody, ELP2 antibody, Elp2 antibody

Background: ELP2 regulates the ligand-dependent activation of STAT3. ELP2 acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
Alias Symbols: FLJ10879, SHINC-2, STATIP1, StIP
Protein Interaction Partner: UBC, FAM96B, CIAO1, PAAF1, WRNIP1, ELP3, NRBP1, CD2AP, KIAA1033, USP34, SNRPB2, PRPSAP2, KIF5B, MMS19, IKBKAP, ELP4, CTDP1, STAT5B, STAT1, JAK2, JAK1, STAT3, TYK2,
Protein Size: 826

Molecular Weight: 92 kDa

Gene ID: 55250

NCBI Accession: NM_018255, NP_060725

UniProt: Q6IA86

Pathways: Stem Cell Maintenance, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus