CHCHD3 antibody (N-Term)

Catalog No. ABIN2787033

Product Details anti-CHCHD3 Antibody

Target: CHCHD3 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 3 (CHCHD3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Sheep, Cow, Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHCHD3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RMKESSPSGS KSQRYSGAYG ASVSDEELKR RVAEELALEQ AKKESEDQKR

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against CHCHD3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHCHD3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 227 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CHCHD3 antibody (ABIN2787033)

Ott, Ross, Straub, Thiede, Götz, Goosmann, Krischke, Mueller, Krohne, Rudel, Kozjak-Pavlovic: "Sam50 functions in mitochondrial intermembrane space bridging and biogenesis of respiratory complexes." in: Molecular and cellular biology, Vol. 32, Issue 6, pp. 1173-88, (2012) (PubMed).

Darshi, Trinh, Murphy, Taylor: "Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space." in: The Journal of biological chemistry, Vol. 287, Issue 47, pp. 39480-91, (2012) (PubMed).

Target Details for CHCHD3

Target: CHCHD3 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 3 (CHCHD3))

Alternative Name: CHCHD3 (CHCHD3 Products)

Synonyms: MINOS3 antibody, PPP1R22 antibody, 0610041L09Rik antibody, 1700039J09Rik antibody, AW558177 antibody, plxna4 antibody, FLJ20420 antibody, wu:fe23h05 antibody, zgc:111837 antibody, si:rp71-18a24.1 antibody, MGC80265 antibody, MGC88973 antibody, coiled-coil-helix-coiled-coil-helix domain containing 3 antibody, coiled-coil-helix-coiled-coil-helix domain containing 3a antibody, coiled-coil-helix-coiled-coil-helix domain containing 3 L homeolog antibody, CHCHD3 antibody, Chchd3 antibody, chchd3a antibody, chchd3.L antibody, chchd3 antibody, LOC100229580 antibody

Background: The function of this protein remains unknown.
Alias Symbols: FLJ20420, MINOS3, PPP1R22
Protein Interaction Partner: NOTCH2NL, SPERT, KRT40, SSX2IP, RAB3IP, LZTS2, USHBP1, CCDC33, GMCL1P1, RPGRIP1, FANCL, SAMM50, SPAG5, CALCOCO2, PDE4DIP, BLZF1, TRAF1, TRIM27, GOLGA2, UBC, GPRASP2, MDM2, SUZ12, RNF2, EZH2, PARK2, HDAC8, NPM1, PAN2, PPP1CA, MYC, FMNL1, MDC1, ECT2, SNRPD3
Protein Size: 227

Molecular Weight: 26 kDa

Gene ID: 54927

NCBI Accession: NM_017812, NP_060282

UniProt: Q9NX63