PNRC2 antibody (N-Term)

Catalog No. ABIN2787027

Product Details anti-PNRC2 Antibody

Target: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Rabbit, Guinea Pig, Horse, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNRC2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MGGGERYNIP DPQSRNASKN QQQHNRQKTK DQNSQMKIVH KKKERGHGYN

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Pnrc2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Rat

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 134 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PNRC2

Target: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Alternative Name: Pnrc2 (PNRC2 Products)

Synonyms: 0610011E17Rik antibody, D4Bwg0593e antibody, wu:cegs2777 antibody, wu:fb51a04 antibody, wu:fb81a06 antibody, wu:fd19g06 antibody, proline rich nuclear receptor coactivator 2 antibody, proline-rich nuclear receptor coactivator 2 antibody, PNRC2 antibody, Pnrc2 antibody, pnrc2 antibody

Background: Pnrc2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. It may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. It is required for UPF1/RENT1 localization to the P-body.It also acts as a nuclear receptor coactivator. It may play a role in controlling the energy balance between energy storage and energy expenditure.
Alias Symbols: MGC93828, Pnrc2
Protein Size: 134

Molecular Weight: 15 kDa

Gene ID: 100125373

NCBI Accession: NM_001103360, NP_001096830

UniProt: Q66HE1