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VPS36 antibody (N-Term)

VPS36 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786923
  • Target See all VPS36 Antibodies
    VPS36 (Vacuolar Protein Sorting 36 (VPS36))
    Binding Specificity
    • 4
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    • 18
    • 10
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
    Host
    • 16
    • 2
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VPS36 antibody is un-conjugated
    Application
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    SNKEPGPFQS SKNSYIRLSF KEHGQIEFYR RLSEEMTQRR WETVPVSQSL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against Vps36. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product VPS36 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 386 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    VPS36 (Vacuolar Protein Sorting 36 (VPS36))
    Alternative Name
    Vps36 (VPS36 Products)
    Synonyms
    C13orf9 antibody, EAP45 antibody, 1700010A24Rik antibody, 2210415M20Rik antibody, 2810408E15Rik antibody, Eap45 antibody, RGD1309754 antibody, fj33d07 antibody, wu:fj33d07 antibody, zgc:55965 antibody, MUG13.23 antibody, MUG13_23 antibody, VPS36 antibody, CG10711 antibody, Dmel\\CG10711 antibody, l(3)L5212 antibody, vps36 antibody, DDBDRAFT_0205116 antibody, DDBDRAFT_0234028 antibody, DDB_0205116 antibody, DDB_0234028 antibody, vacuolar protein sorting 36 homolog antibody, vacuolar protein sorting 36 antibody, vacuolar protein sorting-associated protein 36 antibody, vacuolar protein sorting 36 homolog (S. cerevisiae) antibody, EAP30/Vps36 family protein antibody, Vacuolar protein sorting 36 antibody, vacuolar protein sorting 36 homolog L homeolog antibody, vacuolar protein-sorting-associated protein 36 antibody, ESCRT II complex subunit Vps36 antibody, VPS36 antibody, Vps36 antibody, LACBIDRAFT_399634 antibody, vps36 antibody, AT5G04920 antibody, vps36.L antibody, PTRG_11114 antibody, MCYG_02556 antibody, MGYG_08257 antibody, TERG_05645 antibody, Tsp_04139 antibody
    Background
    Vps36 is a component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.
    Alias Symbols: 1700010A24Rik, 2210415M20Rik, 2810408E15Rik, Eap45
    Protein Interaction Partner: Ubc,
    Protein Size: 386
    Molecular Weight
    42 kDa
    Gene ID
    70160
    NCBI Accession
    NM_027338, NP_081614
    UniProt
    Q91XD6
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