PHYH antibody (Middle Region)

Catalog No. ABIN2786837

Product Details anti-PHYH Antibody

Target: PHYH (Phytanoyl-CoA 2-Hydroxylase (PHYH))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHYH antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EKGDTVFFHP LLIHGSGQNK TQGFRKAISC HFASADCHYI DVKGTSQENI

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against PHYH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PHYH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 338 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PHYH antibody (ABIN2786837)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for PHYH

Target: PHYH (Phytanoyl-CoA 2-Hydroxylase (PHYH))

Alternative Name: PHYH (PHYH Products)

Synonyms: zgc:110203 antibody, LN1 antibody, LNAP1 antibody, PAHX antibody, PHYH1 antibody, RD antibody, AI256161 antibody, AI265699 antibody, Lnap1 antibody, phytanoyl-CoA 2-hydroxylase antibody, phytanoyl-CoA hydroxylase-like antibody, phytanoyl-CoA hydroxylase antibody, PHYH antibody, LOC478001 antibody, phyh antibody, Phyh antibody

Background: This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have b
Alias Symbols: LN1, LNAP1, PAHX, PHYH1, RD
Protein Interaction Partner: FAM9B, UBC, APP, ELAVL1, PHYHIP, FKBP4, ACSL6, TOM1L1, PHYH, PEX7, F8, MAGEA11, WRAP73, COPS3,
Protein Size: 338

Molecular Weight: 39 kDa

Gene ID: 5264

NCBI Accession: NM_006214, NP_006205

UniProt: O14832

Pathways: Monocarboxylic Acid Catabolic Process