QARS antibody (N-Term)

Catalog No. ABIN2786804

Product Details anti-QARS Antibody

Target: QARS (Glutaminyl-tRNA Synthetase (QARS))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Pig, Rabbit, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QARS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DQTLSLMEQL RGEALKFHKP GENYKTPGYV VTPHTMNLLK QHLEITGGQV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against QARS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human QARS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 775 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for QARS

Target: QARS (Glutaminyl-tRNA Synthetase (QARS))

Alternative Name: QARS (QARS Products)

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.
Alias Symbols: GLNRS, PRO2195
Protein Interaction Partner: TCF12, AES, KLC3, DTX2, LZTS2, VPS37B, HUWE1, TRAF4, TRIP13, SUMO2, STAU1, UBC, SUMO1, NEDD8, RNF2, EIF2B3, IQGAP1, AIMP2, VARS, TUBB2A, RPLP0, RPL27A, RPL27, RPL23A, RPL19, RPL15, RPL13, RPL10, RPL7A, RFC4, RARS, PTBP1, PSMC6, NMT1, MRE11A, MARS, IARS, D
Protein Size: 775

Molecular Weight: 88 kDa

Gene ID: 5859

NCBI Accession: NM_005051, NP_005042

UniProt: P47897