SH3G2 antibody (Middle Region)

Catalog No. ABIN2786767

Product Details anti-SH3G2 Antibody

Target: SH3G2 (Endophilin-A1 (SH3G2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3G2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PRREYQPKPR MSLEFPTGDS TQPNGGLSHT GTPKPSGVQM DQPCCRALYD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SH3GL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SH3GL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 352 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SH3G2

Target: SH3G2 (Endophilin-A1 (SH3G2))

Alternative Name: SH3GL2 (SH3G2 Products)

Background: SH3GL2 is implicated in synaptic vesicle endocytosis. SH3GL2 may recruit other proteins to membranes with high curvature.
Alias Symbols: CNSA2, EEN-B1, FLJ20276, FLJ25015, SH3D2A, SH3P4
Protein Interaction Partner: SH3GL1, UBC, ATXN2, EMD, ARNT2, PAXIP1, APP, IPO11, LRRK2, SH3GL3, SH3GL2, TERF1, DNM3, PTPN23, CD2AP, SYNM, PDCD6IP, DYRK1A, DNM2, DNM1, GSTM3, GCH1, F13A1, PPP1R21, ZXDC, PRR14, TMEM108, DPPA4, DACT1, ZNF219, ZNF580, SH3KBP1, TIAM2, EGFL6, MAST2, PPP6R1
Protein Size: 352

Molecular Weight: 40 kDa

Gene ID: 6456

NCBI Accession: NM_003026, NP_003017

UniProt: Q99962

Pathways: Neurotrophin Signaling Pathway, EGFR Downregulation