Pkc beta 1 antibody (N-Term)

Catalog No. ABIN2786693

Product Details anti-Pkc beta 1 Antibody

Target: Pkc beta 1 (Protein Kinase C, beta 1 (Pkc beta 1))

Binding Specificity: N-Term

Reactivity: Rat, Human, Mouse, Rabbit, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pkc beta 1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MADPAAGPPP SEGEESTVRF ARKGALRQKN VHEVKNHKFT ARFFKQPTFC

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PRKCB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRKCB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 673 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Pkc beta 1 antibody (ABIN2786693)

Tatematsu, Yoshimoto, Okajima, Tanizawa, Kuroda: "Identification of ubiquitin ligase activity of RBCK1 and its inhibition by splice variant RBCK2 and protein kinase Cbeta." in: The Journal of biological chemistry, Vol. 283, Issue 17, pp. 11575-85, (2008) (PubMed).

Target Details for Pkc beta 1

Target: Pkc beta 1 (Protein Kinase C, beta 1 (Pkc beta 1))

Alternative Name: PRKCB1 (Pkc beta 1 Products)

Synonyms: PKC-beta antibody, PKCB antibody, PRKCB1 antibody, PRKCB2 antibody, A130082F03Rik antibody, PKC-Beta antibody, Pkcb antibody, Prkcb1 antibody, Prkcb2 antibody, PKC antibody, PRKCB_tv2 antibody, protein kinase C beta antibody, protein kinase C, beta antibody, PRKCB antibody, Prkcb antibody

Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in d
Alias Symbols: MGC41878, PKC-beta, PKCB, PRKCB, PRKCB2, PRKCB1
Protein Interaction Partner: UBC, GNB2L1, MBP, NUMB, PRKCD, MARCKS, LYN, HIST1H1B, SYT6, RB1, PRKCB, TNFRSF1A, PPP2R4, PPP1CA, ITGB2, HSP90AA1, GSK3A, FN1, CASR, RASGRP3, SDC2, CARD11, LMNB1, H1F0, LSP1, HIST1H1A, NCF1, RBCK1, TOP2A, IBTK, KCNA5, RNF31, TERF1, TINF2, EGFR, TRIM41, DD
Protein Size: 673

Molecular Weight: 77 kDa

Gene ID: 5579

NCBI Accession: NM_002738, NP_002729

UniProt: P05771