NPTX2 antibody (Middle Region)

Catalog No. ABIN2786663

Product Details anti-NPTX2 Antibody

Target: NPTX2 (Neuronal Pentraxin II (NPTX2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPTX2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ELEDEKSLLH NETSAHRQKT ESTLNALLQR VTELERGNSA FKSPDAFKVS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against NPTX2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NPTX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 431 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPTX2

Target: NPTX2 (Neuronal Pentraxin II (NPTX2))

Alternative Name: NPTX2 (NPTX2 Products)

Synonyms: NARP antibody, NP-II antibody, NP2 antibody, Narp antibody, np2 antibody, NPTX2 antibody, p50 antibody, nptx2 antibody, neuronal pentraxin 2 antibody, neuronal pentraxin II antibody, neuronal pentraxin 1 antibody, neuronal pentraxin 2a antibody, NPTX2 antibody, Nptx2 antibody, NPTX1 antibody, nptx2a antibody

Background: This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
Alias Symbols: NARP, NP-II, NP2
Protein Interaction Partner: NPTXR, Nptx1,
Protein Size: 431

Molecular Weight: 47 kDa

Gene ID: 4885

NCBI Accession: NM_002523, NP_002514

UniProt: P47972