MAP3K11 antibody (Middle Region)

Catalog No. ABIN2786655

Product Details anti-MAP3K11 Antibody

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K11 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PVGQRSAKSP RREEEPRGGT VSPPPGTSRS APGTPGTPRS PPLGLISRPR

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MAP3K11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAP3K11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 847 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAP3K11

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Alternative Name: MAP3K11 (MAP3K11 Products)

Synonyms: MEKK11 antibody, MLK-3 antibody, MLK3 antibody, PTK1 antibody, SPRK antibody, 2610017K16Rik antibody, Mlk3 antibody, Mlk-3 antibody, RHOE antibody, mitogen-activated protein kinase kinase kinase 11 antibody, MAP3K11 antibody, Map3k11 antibody

Background: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK sig
Alias Symbols: MGC17114, MLK-3, MLK3, PTK1, SPRK, MEKK11
Protein Interaction Partner: STUB1, UBC, HSP90AA1, HSPA4, APP, CDC37, MAP2K7, HSP90AB1, PIN1, GSK3B, GSK3A, EPS8, MAPK8IP1, TRAF6, MAP3K11, CBL, MAP4K2, TRIM5, CLEC4G, TRAF2, COPS5, SH3RF1, MAPK8IP3, MAPK8IP2, KIF3A, IKBKB, RAC1, MAP4K1, CHUK, MAP3K12, RHOG, AKT1, CDC42, MAP2K4, DLG4
Protein Size: 847

Molecular Weight: 93 kDa

Gene ID: 4296

NCBI Accession: NM_002419, NP_002410

UniProt: Q16584

Pathways: MAPK Signaling, Interferon-gamma Pathway