MARK3 antibody (Middle Region)

Catalog No. ABIN2786651

Product Details anti-MARK3 Antibody

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARK3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ATYNGPPASP SLSHEATPLS QTRSRGSTNL FSKLTSKLTR SRNVSAEQKD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against MARK3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MARK3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 729 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MARK3

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Alternative Name: MARK3 (MARK3 Products)

Background: MARK3 is involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'.
Alias Symbols: CTAK1, KP78, PAR1A, Par-1a
Protein Interaction Partner: Crtc2, UBC, MAPT, YWHAZ, YWHAH, YWHAG, YWHAE, YWHAB, YWHAQ, SFN, ASB13, TCEA2, PIM1, MARK3, CDC25C, KSR1, USP21, PKP2, MAP2, MITF, PRKAA1, TADA2A, TERF2, HDAC7, HDAC5, HDAC4, MARK2, SAAL1, ANKRD7, VPS11, PNPLA2, NOL11, PMPCB, CHGB, FANCF, CPSF4, DYNLL1, P
Protein Size: 729

Molecular Weight: 81 kDa

Gene ID: 4140

NCBI Accession: NM_002376, NP_002367

Pathways: SARS-CoV-2 Protein Interactome