PPP2R2D antibody (C-Term)
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- Target See all PPP2R2D Antibodies
- PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))
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Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PPP2R2D antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RRDVTLEASR ENSKPRASLK PRKVCTGGKR KKDEISVDSL DFNKKILHTA
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against Ppp2r2d. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product PPP2R2D Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 453 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))
- Alternative Name
- Ppp2r2d (PPP2R2D Products)
- Synonyms
- 1300017E19Rik antibody, D7Ertd753e antibody, MDS026 antibody, protein phosphatase 2, regulatory subunit B, delta antibody, protein phosphatase 2 regulatory subunit Bdelta antibody, protein phosphatase 2 regulatory subunit B, delta S homeolog antibody, Ppp2r2d antibody, PPP2R2D antibody, ppp2r2d.S antibody
- Background
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Ppp2r2d is a B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.
Alias Symbols: 1300017E19Rik, D7Ertd753e, MDS026
Protein Interaction Partner: Supt5, SMURF1, SMAD3, SMAD2,
Protein Size: 453 - Molecular Weight
- 50 kDa
- Gene ID
- 52432
- NCBI Accession
- NM_026391, NP_080667
- UniProt
- Q925E7
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