BLVRB antibody (Middle Region)

Catalog No. ABIN2786523

Product Details anti-BLVRB Antibody

Target: BLVRB (Flavin Reductase (BLVRB))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Dog, Guinea Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLVRB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GLKYVAVMPP HIGDQPLTGA YTVTLDGRGP SRVISKHDLG HFMLRCLTTD

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against BLVRB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BLVRB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 206 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-BLVRB antibody (ABIN2786523)

Clunie, Clark, Mortimer, Stephenson, Aitken, Smith, Sherwin, Archer: "Evaluating bone health in women with oestrogen receptor positive breast cancer (ERBC) starting aromatase inhibitors." in: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, Vol. 35, Issue 5, pp. 475-80, (2009) (PubMed).

Target Details for BLVRB

Target: BLVRB (Flavin Reductase (BLVRB))

Alternative Name: BLVRB (BLVRB Products)

Synonyms: BVRB antibody, FLR antibody, SDR43U1 antibody, biliverdin reductase B (flavin reductase (NADPH)) antibody, biliverdin reductase B antibody, Blvrb antibody, BLVRB antibody

Background: BLVRB catalyzes electron transfer from reduced pyridine nucleotides to flavins as well as methylene blue, pyrroloquinoline quinone, riboflavin, or methemoglobin. BLVRB has possible role in protecting cells from oxidative damage or in regulating iron metabolism. In the liver, BLVRB converts biliverdin to bilirubin.
Alias Symbols: BVRB, FLR, MGC117413, SDR43U1
Protein Interaction Partner: SUMO1, NEDD8, UBC, RPL31, ORM1, GMDS, HMOX1,
Protein Size: 206

Molecular Weight: 22 kDa

Gene ID: 645

NCBI Accession: NM_000713, NP_000704

UniProt: P30043