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PPOX antibody (C-Term)
PPOX
Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse, Dog
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PPOX Antibody
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Target
See all PPOX Antibodies
PPOX
(Protoporphyrinogen Oxidase (PPOX))
Binding Specificity
All epitopes for PPOX antibodies
C-Term
Reactivity
All reactivities for PPOX antibodies
Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse, Dog
Host
All hosts for PPOX antibodies
Rabbit
Clonality
All clonalities for PPOX antibodies
Polyclonal
Conjugate
All conjugates for PPOX antibodies
This PPOX antibody is un-conjugated
Application
All applications for PPOX antibodies
Western Blotting (WB)
Sequence
GGALHALPTG LRGLLRPSPP FSKPLFWAGL RELTKPRGKE PDETVHSFAQ
Predicted Reactivity
Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Characteristics
This is a rabbit polyclonal antibody against PPOX. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of human PPOX
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for PPOX
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Target
PPOX
(Protoporphyrinogen Oxidase (PPOX))
Alternative Name
PPOX (PPOX Products )
Synonyms
PPO antibody, V290M antibody, VP antibody, Ppo antibody, BcDNA:LD41392 antibody, CG5796 antibody, Dmel\\CG5796 antibody, ESTS:9F2T antibody, zgc:123252 antibody, HEMG1 antibody, PPO1 antibody, PROTOPORPHYRINOGEN OXIDASE antibody, TC0121 antibody, hemG antibody, protoporphyrinogen oxidase antibody, Protoporphyrinogen oxidase antibody, Flavin containing amine oxidoreductase family antibody, polyphenol oxidase, chloroplastic antibody, PPOX antibody, Ppox antibody, ppox antibody, hemY antibody, TC_RS00645 antibody, Mrub_1406 antibody, Mesil_2992 antibody, Trad_0583 antibody, Calni_0746 antibody, Ocepr_1049 antibody, Tmar_0766 antibody, Intca_1907 antibody, Despr_0642 antibody, Plabr_2407 antibody, Deipr_2130 antibody, Hipma_0622 antibody, LOC110782963 antibody
Background
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified. Alias Symbols: VP, PPO, V290M Protein Size: 158
Molecular Weight
17 kDa
Gene ID
5498
NCBI Accession
NM_000309 , NP_000300
UniProt
P50336
Pathways
Synaptic Membrane , Feeding Behaviour
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