PEPD antibody (Middle Region)

Catalog No. ABIN2786507

Product Details anti-PEPD Antibody

Target: PEPD (Peptidase D (PEPD))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Cow, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEPD antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LGAVFMPHGL GHFLGIDVHD VGGYPEGVER IDEPGLRSLR TARHLQPGMV

Predicted Reactivity: Cow: 92%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PEPD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PEPD

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 493 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PEPD antibody (ABIN2786507)

Surazynski, Donald, Cooper, Whiteside, Salnikow, Liu, Phang: "Extracellular matrix and HIF-1 signaling: the role of prolidase." in: International journal of cancer. Journal international du cancer, Vol. 122, Issue 6, pp. 1435-40, (2008) (PubMed).

Target Details for PEPD

Target: PEPD (Peptidase D (PEPD))

Alternative Name: PEPD (PEPD Products)

Background: Xaa-Pro dipeptidase is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus (but not Pro-Pro). It is important in collagen metabolism because of the high levels of iminoacids.Xaa-Pro dipeptidase is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus (but not Pro-Pro). It is important in collagen metabolism because of the high levels of iminoacids. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-74 DC395475.1 1-74 75-101 DC385464.1 1-27 102-2018 BC015027.1 1-1917
Alias Symbols: MGC10905, PROLIDASE
Protein Interaction Partner: USP7, SUMO1, NDRG1, NAMPT, DPP3, CTSA, MVD, EIF6, GSR, GNS, GLS, GBP2, EIF5A, EIF4E, DLD, CASP7, CAPN1, ASS1, NHLRC2, LDHAL6B, FTO, BCCIP, CNDP2, GINS2, GDA, KYNU, RPS6KA1, SPP1, UBC, ATXN1, CUL2, TERF1, PEPD,
Protein Size: 493

Molecular Weight: 54 kDa

Gene ID: 5184

NCBI Accession: NM_000285, NP_000276

UniProt: P12955