ALOX15 antibody (Middle Region)

Catalog No. ABIN2786489

Product Details anti-ALOX15 Antibody

Target: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALOX15 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QHASVHLGQL DWYSWVPNAP CTMRLPPPTT KDATLETVMA TLPNFHQASL

Predicted Reactivity: Cow: 92%, Dog: 93%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against ALOX15. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ALOX15

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 662 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ALOX15 antibody (ABIN2786489)

Wieczfinska, Kacprzak, Pospiech, Sokolowska, Nowakowska, Pniewska, Bednarek, Kuprys-Lipinska, Kuna, Pawliczak: "The whole-genome expression analysis of peripheral blood mononuclear cells from aspirin sensitive asthmatics versus aspirin tolerant patients and healthy donors after in vitro aspirin challenge." in: Respiratory research, Vol. 16, pp. 147, (2015) (PubMed).

Target Details for ALOX15

Target: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Alternative Name: ALOX15 (ALOX15 Products)

Synonyms: 15-LOX-1 antibody, 15LOX-1 antibody, ALOX15 antibody, 12-LO antibody, Alox12l antibody, L-12LO antibody, 12-LOX antibody, Alox12 antibody, ALOX12 antibody, 15-LOX antibody, Alox12e antibody, arachidonate 15-lipoxygenase antibody, Arachidonate 15-lipoxygenase antibody, ALOX15 antibody, Alox15 antibody, Nmul_A0532 antibody, Sden_1680 antibody, Swoo_2919 antibody, PCC8801_3106 antibody, Cyan8802_3014 antibody, Nwat_1315 antibody

Background: ALOX15 converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. ALOX15 also acts on C-12 of arachidonate as well as on linoleic acid.
Alias Symbols: 15-LOX2, 15LOX-1, 15-LOX-1
Protein Size: 662

Molecular Weight: 73 kDa

Gene ID: 246

NCBI Accession: NM_001140, NP_001131

UniProt: P16050

Pathways: Regulation of Actin Filament Polymerization